Ketone bodies are produced by the body to provide fuel during fasting, and are thought to have roles in regulating cellular processes and aging mechanisms beyond energy production. Research by Buck Institute scientists, including experiments in the nematode Caenorhabditis elegans, and in mouse models, provides what they suggest is a direct molecular mechanism for the regulation of misfolded proteins by ketone bodies and related metabolites. The results, they said, indicate that ketone bodies, in...