RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential—not 'junk'
Credit: Pixabay/CC0 Public Domain
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of the remaining 98% remains largely unknown.
One pressing problem in human genetics is to understand what these regions of the genome do—if anything at all. Historically, some have even referred to these regions as "junk."
Now, a study in Cell f...
Read more at phys.org