Undruggable No More – Advances for Targeting Mutant Ras Proteins and Cancer
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By Anne-Sophie Ay-Berthomieu, Ph.D.
May 17, 2022
Table of Contents:
Introduction
Ras History: From Retrovirus Research to Cancer Research
Ras: a Major Driver of Carcinogenesis
Ras: a Diagnostic and Prognostic Biomarker
Ras: a Druggable Therapeutic Target
Summary
Introduction
Ras is a small GTPase protein of 21kDa, seeming insignificant in size, but with a very unique destiny. Ras was first discovered in retroviruses where it was found to be involved in the ...
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