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Undruggable No More – Advances for Targeting Mutant Ras Proteins and Cancer

<< Back to MOTIFvations Blog Home Page By Anne-Sophie Ay-Berthomieu, Ph.D. May 17, 2022 Table of Contents: Introduction Ras History: From Retrovirus Research to Cancer Research Ras: a Major Driver of Carcinogenesis Ras: a Diagnostic and Prognostic Biomarker Ras: a Druggable Therapeutic Target Summary Introduction Ras is a small GTPase protein of 21kDa, seeming insignificant in size, but with a very unique destiny. Ras was first discovered in retroviruses where it was found to be involved in the ...

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