Dear Editor,Type 2 diabetes (T2D) typically starts with insulin resistance in peripheral tissues and proceeds with gradual loss of islet function due to the reduction in β-cell mass or dedifferentiation of β cells1,2. More than 30% of T2D patients eventually rely on exogenous insulin treatment. Cadaveric islet transplantation is an effective treatment for insulin-dependent diabetes3,4. Notably, improved metabolic control after islet transplantation is associated with better kidney allograft func...