Scientists at UC Berkeley develop CRISPR technique that selectively destroys cancer cells with p53 mutation found in 50% of cancers, targeting previously undruggable ovarian, pancreatic and lung cancers by shredding chromatin.

New CRISPR Technique Selectively Shreds Cancer Cells, Including “Undruggable” Cancers

Innovative chromatin shredding technique shown to selectively destroy cancer cells carrying a mutation found in nearly half of all cancer casesThe job of a tumor suppressor protein is right in the name: stopping us from getting cancer at the cellular level. But when they’re not working properly, the cell is left with limited defenses. In a new paper published today in the journal Nature titled “Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding,“ researchers at the Innova...