“Reconstructing Psychopathology: A data-driven reorganization of the symptoms in DSM-5” by Miri Forbes, et al. (was available as a preprint at the time of writing this post, later published in Clinical Psychological Science) is a brilliantly designed and innovative study of the quantitative structure of psychopathology with important ramifications for our understanding of psychiatric classification. No one has conducted a study quite like this before, and the results are remarkable. It takes pla...